Diaper rash can happen from time to time, even with superabsorbent diaper technology and frequent diaper changes. It's worth having a good diaper rash cream on hand to help settle your little one’s skin and help prevent the condition from reoccurring. To help you choose the best diaper rash cream for your baby, we surveyed more than 8,000 Pampers Parents and put together a list of their top product choices.

Read on for a list of their favorite diaper rash creams, plus some tips on how to treat and prevent diaper rash, and what causes it in the first place.

What Is Diaper Rash and What Causes It?

Diaper rash is a rash that can appear around your baby’s diaper area. It usually makes your baby’s skin red and tender. It’s sometimes accompanied by red bumps, scaly skin, and — in more severe cases — blisters or open sores.

Diaper rash often forms when urine or poop irritates your baby’s skin, such as when she’s been in a wet or dirty diaper a little too long. However, there are several other potential causes of diaper rash, including:

  • A diaper that’s too tight

  • A diaper that chafes against your baby’s skin

  • An allergic reaction to certain soaps, laundry detergents, fragrances, baby wipes, or even certain foods

  • A skin infection caused by fungi or bacteria

  • Your baby is taking antibiotics, which can lead to the overgrowth of yeast causing a yeast infection.

In addition to using a diaper rash cream, there are other things you can do to treat diaper rash, which we cover in detail at the end of this article.

Types of Diaper Rash Creams and Ointments

Diaper rash creams often have a base ingredient of either petroleum jelly or zinc oxide, both of which serve as a barrier to protect the skin from damaging moisture. You might want to experiment with the different base ingredients to see what works best for your baby. For example, Aquaphor is a classic petroleum-jelly-based product, and Desitin is a well-known zinc-oxide-based product.

Other ingredients are sometime added, among them aloe vera and calendula, which one study has shown to be effective in treating diaper rash.

If your baby’s diaper rash is more severe or is caused by a yeast infection, your baby’s healthcare provider may recommend or prescribe a special cream or ointment such as a gentle hydrocortisone cream (a steroid cream), an antifungal cream, or an antibiotic.

Before applying a cream, talk with your baby’s healthcare provider about which diaper rash cream might be best for your little one.

“You don’t want something that your baby’s sensitive skin can’t handle. Just because it is made for babies doesn’t mean that it’s made for YOUR baby.”

PAMPERS PARENT

8 Best Diaper Rash Creams and Ointments

More than 8,000 Pampers Parents voted for the best diaper rash creams. Here are the top 8 creams chosen by Pampers Parents:

1. Desitin Daily Defense Baby Diaper Rash Cream

Why pick this one? This diaper rash cream was the top favorite among surveyed Pampers Parents. It can be used to treat and soothe diaper rash, and if your little one is prone to diaper rash, this is a good product to use every day to help prevent it, too.

With a base ingredient of zinc oxide, this cream provides your baby’s bottom with a protective barrier against the things that may cause or aggravate diaper rash.

Highlights: The hypoallergenic formula is free of parabens, phthalates, dyes, and added fragrances.

Details:

Desitin Daily Defense Baby Diaper Rash Cream
Item weight 16 ounces
Base ingredient Zinc oxide

Price*: about $12.34 on Amazon.com

Pampers Parents pros and cons:

  • Pros: It works quickly and it’s easy to wipe off when needed.

  • Cons: It tends to spread out rather than staying on the area where it’s applied, so it can get messy

2. Aquaphor Baby Healing Ointment Advanced Therapy Skin Protectant

Why pick this one? The ointment is formulated with 41 percent petrolatum (another term for petroleum jelly) as well as moisturizing ingredients like panthenol and glycerin to help nourish and protect your baby’s skin.

This ointment can also be used for many other issues such as chapped skin, drool rash, and minor cuts or scrapes. It can help protect skin from getting overly dried from wind and cold weather, too. Your whole family could end up using this ointment.

Aquaphor isn’t harsh on the skin and I love that it’s not perfumed in any way.

Pampers Parent

Highlights: This ointment is formulated without fragrances and preservatives.

Details:

Aquaphor Baby Healing Ointment Advanced Therapy Skin Protectant
Item weight 2-pack, 14 ounces each
Base ingredient Petroleum jelly

Price*: about $70.50 on Amazon.com

Pampers Parents pros and cons:

  • Pros: It’s clear and it doesn’t dry up and get stuck on the diaper rash.

  • Cons: It feels greasy.

3. Boudreaux’s Butt Paste Diaper Rash Ointment

Why pick this one? This diaper rash ointment helps soothe the discomfort of diaper rash. It’s a thick paste that’s good for treating mild diaper rash. It’s made with a 16 percent zinc oxide base.

It might be of interest to know that this diaper rash formula was originally created by a pharmacist and father of four for his own little ones.

Highlights: This formula doesn’t include dyes, preservatives, parabens, or talc.

Details:

Boudreaux’s Butt Paste Diaper Rash Ointment
Item weight 3-pack, 4 ounces each
Base ingredient Zinc oxide

Price*: about $21.06 on Amazon.com

Pampers Parents pros and cons:

  • Pros: It’s thick, but easy enough to apply.

  • Cons: It’s not easy to wash off if it gets on your hands.

4. A+D Original Diaper Rash Ointment

Why pick this one? This ointment is made with lanolin to help protect your little one’s skin from wetness, and therefore helps treat and prevent diaper rash. It’s also made with vitamins A and D. This formula is free from parabens, phthalates, and dyes.

Highlights: This formula goes on easily and can be used on your own skin and lips to relieve dry, chapped skin.

Details:

A+D Original Diaper Rash Ointment
Item weight 16 ounces
Base ingredient Petroleum jelly

Price*: about $10.42 on Amazon.com

Pampers Parents pros and cons:

  • Pros: It stays on for a long time.

  • Cons: It has a medicinal odor that might bother some people

5. Burt’s Bees Baby 100% Natural Diaper Ointment

Why pick this one? This formula is made with 40 percent zinc oxide and almond oil. It creates a softening and soothing layer on your baby’s skin to protect it from wetness.

It’s thick and stays put, but also wears off with time so it doesn’t cake onto the skin.

Pampers Parent

Highlights: This 100 percent natural formula has no phthalates, parabens, or sodium laurel sulfates.

Details:

Burt’s Bees Baby 100% Natural Diaper Ointment
Item weight 2-pack, 3 ounces each
Base ingredient Zinc oxide

Price*: about $16.09 on Amazon.com

Pampers Parents pros and cons:

  • Pros: It’s all natural and doesn’t smell.

  • Cons: It doesn’t seem to help with more stubborn rashes.

6. Balmex Complete Zinc Oxide Protection Diaper Rash Cream

Why pick this one? This formula goes on smoothly and is easy to wipe off, so it won’t irritate your baby’s skin further during diaper changes.

Highlights: This formula is made with aloe and vitamin E to help ease your little one’s discomfort.

Details:

Balmex Complete Zinc Oxide Protection Diaper Rash Cream
Item weight 16 ounces
Base ingredient Zinc oxide

Price*: about $12.99 on Amazon.com

Pampers Parents pros and cons:

  • Pros: It smells great and you can get quick results with this cream.

  • Cons: It comes out sticky like toothpaste.

7. Earth Mama Organic Diaper Balm

Why pick this one? Unlike most diaper rash creams, this one isn’t made with either a zinc oxide base or a petroleum jelly base. It’s formulated with beeswax and calendula. It’s also made with several other soothing oils like olive oil and shea butter.

This formula also contains tea tree oil, which is thought to have antibacterial properties.

Highlights: This is the only organic diaper rash cream on this Pampers Parents’ top list.

Details:

Earth Mama Organic Diaper Balm
Item weight 3-pack, 2 ounces each
Base ingredient Organic olive oil

Price*: about $16.09 on Amazon.com

Pampers Parents pros and cons:

  • Pros: It has natural ingredients that are familiar and not questionable to put on your baby’s skin.

  • Cons: It’s on the pricey side compared to some other diaper rash creams.

8. Cetaphil Baby Diaper Cream with Organic Calendula

Why pick this one? This zinc oxide diaper rash cream includes organic calendula. This cream is free of parabens, colorants, and mineral oils.

Highlights: This diaper rash cream is free of additives to minimize the risk of an allergic reaction.

Details:

Cetaphil Baby Diaper Cream With Organic Calendula
Item weight 2.5 ounces
Base ingredient Zinc oxide

Price*: about $7.38 on Amazon.com

Pampers Parents pros and cons:

  • Pros: It doesn’t dry out the skin.

  • Cons: It doesn’t work well for moderate rashes. It’s better for mild rashes.

How to Treat Diaper Rash

Here are a few steps you can take to help treat and maybe even prevent diaper rash:

  • Changing your baby’s diaper more often is typically the best way to clear up diaper rash.

  • Use superabsorbent, disposable diapers (particularly if you’re treating diaper rash).

  • Clean your baby’s bottom carefully and gently during each diaper change. Use fragrance-free and alcohol-free wipes or rinse your baby’s bottom with warm water.

  • Ideally, let your baby’s bottom air-dry. If not, pat your baby’s bottom completely dry after cleaning it during a diaper change.

  • Apply a thick layer of diaper rash cream or ointment. You might like to get your baby’s healthcare provider’s advice about how to apply diaper rash cream, especially if he’s prescribed a cream for a more severe diaper rash.

  • Make sure your baby’s diapers fit properly. If they’re too tight, there isn’t enough airflow, the diaper might chafe against the skin, and urine or poop might be held against your baby’s skin — all of which can increase the risk of diaper rash.

  • Connect with your baby’s healthcare provider to get advice, especially if the diaper rash doesn’t clear up within 48 to 72 hours, or if it gets worse.

When your little one has diaper rash, it’s usually something that you can quickly treat and heal with a few simple steps or the help of your baby’s healthcare provider. We hope that one of these great diaper rash creams that come recommended by other Pampers Parents does the trick for you and your little one!

Learn more about the most common baby rashes, and find out what you can do to treat them.

Recall Notice

Before buying a product, always check that it’s approved and hasn’t been recalled on sites like the Juvenile Products Manufacturers Association and the U.S. Consumer Product Safety Commission (CPSC).

*Prices are correct at the time of writing.

How We Got These Results

We surveyed thousands of parents in the Pampers Community and asked them to choose the products they love the most, and to share their views on specific products and product categories.

Based on the survey responses, we have taken the top product picks and added our own research to create this article. The aim is to help you choose the right product for you and your family. We might receive commissions on purchases made from the links in this article, but the products featured are the Pampers Community’s top choices.

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