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  1. neonatal-biology-vulnerable-populations

Neonatal Biology & Vulnerable Populations

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Mom holding her baby's hand while the baby looks away from the camera.

Epidermal Immunity and Function: Origin in Neonatal Skin

Baby's Skin Is Uniquely Designed to Protect and Grow — And Pampers Science Is Helping to Understand It. Pampers scientists have published their research findings in (Frontiers in Molecular Biosciences, June 2022). Your baby's skin is far more than a soft, delicate surface — it's a remarkable, actively developing organ engineered by nature to protect, adapt, and grow. Pampers scientists, together with leading dermatology researchers, are decoding how infant skin works: from the protective vernix coating that shields babies in the womb, to the rapid transition from a wet to a dry environment after birth. By just 2–3 months of age, a baby's skin already contains higher levels of skin-building proteins and natural moisturizing factors than adult skin, with genes actively prioritizing growth and renewal. That's why every Pampers diaper is thoughtfully designed with breathable materials, super-absorbent core, and emollient-enriched liners — gently supporting the extraordinary biology of your baby's developing skin.

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Pre-Term twins laying skin-to-skin with mom

Improving Diaper Performance for Extremely Low-Birth-Weight Infants

Pampers is committed to meeting the unique needs of NICU babies with the most sensitive skin. Research published in Clinical Pediatrics (Sanchez et al., 2018), gathered crucial insights from NICU nurses on designing diapers for Extremely Low-Birth-Weight (ELBW) infants. This study validated that 93% of nurses preferred Pampers' test diaper, specifically engineered for ELBW babies’ sensitive skin and developmental needs, over their current diaper routine. This demonstrates Pampers’ dedication to responsive innovation that supports optimal fit, positioning, and skin health for even the tiniest infants.

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Baby holding their mom's thumb while being cradled by their mom.

Clinical Effects of Diaper Types on the Skin of Normal Infants and Infants with Atopic Dermatitis

Every baby deserves skin care that's gentle enough for even the most delicate skin. For nearly 40 years, Pampers scientists have led that mission starting with the world's first clinical study of diapers on babies with eczema (Journal of the American Academy of Dermatology, Seymour et al., 1987), which demonstrated the skin benefits of Pampers' pioneering super-absorbent core. Today's Pampers diapers have continued to innovate from this research.

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Baby in the NICU with parent's hands inside the isolette to comfort them.

Skin Care in the NICU Patient: Effects of Wipes versus Cloth and Water on Stratum; Corneum Integrity

Fun Fact! For newborns, Pampers Sensitive wipes are as gentle as plain cotton and water on babies delicate skin and have added benefits for the skin, too! In a landmark study in Neonatology (Visscher, Odio et al., 2009), an independent hospital research showed among preterm newborns in the NICU that Pampers Sensitive Wipes are gentle enough for the most fragile babies. Pampers wipes with emollient cleansers reduced skin redness, strengthened the skin barrier, and supported babies natural healthy skin pH better than cloth and water. That's why Pampers Sensitive Wipes are trusted in neonatal intensive care units, because they're a safe, gentle choice for your baby's everyday diaper changes at home.

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