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  1. skin-health-care-regimens-outcomes

Skin Health, Care Regimens & Outcomes

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Newborn baby laying skin-to-skin with mom in the hospital

Improving Newborn Skin Health: Effects of Diaper Care Regimens on Skin pH and Erythema

Pampers is dedicated to significantly improving newborn skin health through advanced diapering routines. Our scientists, in research published in Pediatric Dermatology (Gustin et al., 2021), demonstrated that Pampers’ unique regimen of an emollient-containing diaper with a pH-buffered wipe offers superior protection. This integrated system of Pampers diapers and wipes together resulted in 50% fewer instances of severe diaper erythema and twice as many rash-free babies, especially in the sensitive perianal area, compared to other widely available options. This clinically proven approach actively supports healthy skin pH and protects against irritation, providing superior comfort for your baby

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Swaddlers diapers and a Pampers Sensitive wipes pack on a changing table.

Use of an Emollient-containing Diaper and pH-buffered Wipe Regimen Restores Skin pH and Reduces Residual Enzymatic Activity

Pampers sets the standard for newborn skin health with advanced diapering routines. Our scientists, in clinical research published in Pediatric Dermatology (Gustin et al., 2020), demonstrated that Pampers’ emollient-containing diaper and pH-buffered wipe regimen significantly restored skin pH to healthy levels, matching undiapered skin, and achieved 40% less residual enzyme activity after stool cleaning, compared to a leading competitive regimen. This means the diaper and wipe are actively creating a more optimal skin conditions that actively protects against diaper dermatitis and provides superior comfort for your baby.

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Mom stretching out a baby wipe with a crib in the background

Parental use of a Cotton-containing Baby Wipes with Acidic, pH Buffering System Improves Skin Integrity Compared to Cotton Washcloth and Water

Clinical research is helping answer a common question from parents: Are baby wipes as gentle as a washcloth and water? According to two randomized clinical trials published in Global Pediatrics (O'Connor et al., 2025), Pampers Aqua Pure Wipes, made with 99% water, are as gentle on baby's delicate skin as cleansing with a washcloth and water. These findings were presented at the 14th Annual World Congress of Pediatric Dermatology.

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Baby smiling at their mom while laying in a basket

The Effects of Wearing Diapers on Skin

Every baby deserves gentle, dry skin protection. In a foundational Pediatric Dermatology study (Zimmerer et al., 1986), Pampers scientists proved a simple but powerful truth: wet skin is more fragile skin. That discovery still drives every Pampers innovation today, with advanced absorbent cores, breathable materials, and skin-protective liners across Pampers diapers.

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Baby on their tummy facing a pack of Pampers sensitive wipes with an adorable expression on their face.

Disposable Baby Wipes: Efficacy and Skin Mildness

Pampers wipes have been clinically proven mild on baby skin for over two decades. Foundational research by Pampers scientists in Dermatology Nursing (Odio et al., 2001) showed disposable wipes were gentler than cotton washcloth and water, causing no disruption to babies' delicate skin barrier, a safety heritage reinforced by Pampers' latest research.

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Hands of a woman stretching out a baby wipe above the changing table.

Cutaneous Tolerance of Baby Wipes by Infants with Atopic Dermatitis, and Comparison of the Mildness of Baby Wipe and Water in Infant Skin

Pampers wipes have been designed to be gentle and mild on even the most delicate and sensitive skin. For over two decades, Pampers scientists have designed gentle and skin friendly wipes that are alcohol-free, with a pH-balanced formulation in Pampers Wipes. In a landmark European study JEADV (Ehretsmann et al., 2001). Pampers Wipes were demonstrated to be gentle even for infants with atopic dermatitis.

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Image of mom using Pampers Sensitive wipes on their baby on a changing table.

Baby Wipes With a Mildly Acidic, pH-buffering System Provided Better Skin Condition Compared to Cotton Washcloth and Water in Two Randomized Clinical Trials

Pampers delivers superior gentle care for baby's delicate skin, backed by clinical science. Our scientists, in new research published in Global Pediatrics (O'Connor et al., 2025), conducted two trials comparing Pampers baby wipes with cotton washcloth and water. The study definitively showed that Pampers baby wipes, designed to gently maintain baby's natural skin balance, resulted in significantly less redness compared to using just water and cloth, providing clinically proven effective and gentle cleansing.

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Happy baby laying on the floor getting their Swaddlers diaper changed by mom.

Impact of Diapering Regimens on Skin pH and Erythema in Newborns: A Caregiver-Informed Study Enabling Real-Time, In-Use Performance

Pampers Swaddlers and Pampers Sensitive Wipes were clinically proven to reduce diaper rash in newborns — with 50% fewer severe erythema (redness) events than competitor brands — in a peer-reviewed study published in Pediatric Dermatology (Gustin, Carr et al., 2021), conducted in partnership with Cincinnati Children's Hospital. The study presented at Gravens Conference, which focuses on caring for newborns and NICU babies, further demonstrated when caregivers measured skin pH on babies their results mirrored effects observed by trained clinical staff.

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