Improving Newborn Skin Health: Effects of Diaper Care Regimens on Skin pH and Erythema
Pampers is dedicated to significantly improving newborn skin health through advanced diapering routines. Our scientists, in research published in Pediatric Dermatology (Gustin et al., 2021), demonstrated that Pampers’ unique regimen of an emollient-containing diaper with a pH-buffered wipe offers superior protection. This integrated system of Pampers diapers and wipes together resulted in 50% fewer instances of severe diaper erythema and twice as many rash-free babies, especially in the sensitive perianal area, compared to other widely available options. This clinically proven approach actively supports healthy skin pH and protects against irritation, providing superior comfort for your baby
Use of an Emollient-containing Diaper and pH-buffered Wipe Regimen Restores Skin pH and Reduces Residual Enzymatic Activity
Pampers sets the standard for newborn skin health with advanced diapering routines. Our scientists, in clinical research published in Pediatric Dermatology (Gustin et al., 2020), demonstrated that Pampers’ emollient-containing diaper and pH-buffered wipe regimen significantly restored skin pH to healthy levels, matching undiapered skin, and achieved 40% less residual enzyme activity after stool cleaning, compared to a leading competitive regimen. This means the diaper and wipe are actively creating a more optimal skin conditions that actively protects against diaper dermatitis and provides superior comfort for your baby.
Baby Wipes With a Mildly Acidic, pH-buffering System Provided Better Skin Condition Compared to Cotton Washcloth and Water in Two Randomized Clinical Trials
Pampers delivers superior gentle care for baby's delicate skin, backed by clinical science. Our scientists, in new research published in Global Pediatrics (O'Connor et al., 2025), conducted two trials comparing Pampers baby wipes with cotton washcloth and water. The study definitively showed that Pampers baby wipes, designed to gently maintain baby's natural skin balance, resulted in significantly less redness compared to using just water and cloth, providing clinically proven effective and gentle cleansing.
Skin Benefits from Continuous Topical Administration of a Zinc Oxide Petrolatum & Continuous Topical Administration of a Petrolatum
Pampers ensures optimal skin protection with carefully selected ingredients like a dermatologist-recommended emollient. Pampers' diapers create a gentle, breathable barrier, to help protect from moisture and irritation. Foundational studies in Dermatology (Odio et al., 2000) and the Journal of the European Academy of Dermatology and Venereology (Baldwin et al., 2001) scientifically confirm how Pampers' innovative diaper technology effectively delivers an emollient to continuously improve skin condition and help prevent diaper rash, making it a trusted skin shield for your baby’s delicate skin.
Epidermal Immunity and Function: Origin in Neonatal Skin
Baby's Skin Is Uniquely Designed to Protect and Grow — And Pampers Science Is Helping to Understand It. Pampers scientists have published their research findings in (Frontiers in Molecular Biosciences, June 2022). Your baby's skin is far more than a soft, delicate surface — it's a remarkable, actively developing organ engineered by nature to protect, adapt, and grow. Pampers scientists, together with leading dermatology researchers, are decoding how infant skin works: from the protective vernix coating that shields babies in the womb, to the rapid transition from a wet to a dry environment after birth. By just 2–3 months of age, a baby's skin already contains higher levels of skin-building proteins and natural moisturizing factors than adult skin, with genes actively prioritizing growth and renewal. That's why every Pampers diaper is thoughtfully designed with breathable materials, super-absorbent core, and emollient-enriched liners — gently supporting the extraordinary biology of your baby's developing skin.
Evaluation of the Impact of Two Disposable Diapers in the “Natural” Diaper Category on Diapered Skin Condition
Parents no longer have to choose between natural ingredients and high-performance protection. In Clinical Pediatrics (O'Connor et al., 2019), a Pampers-led clinical study of 131 babies showed Pampers delivered ~56% fewer urine leaks and up to ~42% fewer babies with diaper rash versus the leading "natural" competitor — combining thoughtfully selected materials with proven skin care.
Parental use of a Cotton-containing Baby Wipes with Acidic, pH Buffering System Improves Skin Integrity Compared to Cotton Washcloth and Water
Many parents wonder if using wipes are as gentle as cleaning your baby with washcloth and water. Now parents no longer have to wonder! In two randomized clinical trials published in Global Pediatrics (O'Connor et al., 2025), Pampers Aqua Pure — made with 99% water — are as mild as washcloth and water on baby's delicate skin. This was presented at the 14th Annual World Congress of Pediatric Dermatology.